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Risk of major congenital malformations in relation to maternal overweight and obesity severity: cohort study of 1.2 million singletons

BMJ 2017; 357 doi: https://doi.org/10.1136/bmj.j2563 (Published 14 June 2017) Cite this as: BMJ 2017;357:j2563

Consequences of Maternal Obesity

Re: Risk of major congenital malformations in relation to maternal overweight and obesity severity: cohort study of 1.2 million singletons Martina Persson,1,2 Sven Cnattingius,1 Eduardo Villamor,1,3 Jonas Söderling,1 Björn Pasternak,1,4 Olof Stephansson,1,5 Martin Neovius1 doi:10:1136/bmj.j2563 (Persson et al.)

Overweight and obesity have estimated to have caused about 3.4 million deaths worldwide in 2010 (Ng et al). Obesity seriously impacts fetal and neonatal outcomes (Arabin and Stupin). Maternal obesity is often associated with increased risk of adverse health conditions to both mother and fetus (Carmichael, Rasmussen, and Shaw). The best window opportunity to prevent complications associated with maternal obesity is through interventions such as pre-conception assessment and counseling (Iessa and Bérard). Women within the child bearing age should be informed of the importance of having a healthy lifestyle before getting pregnant.

Competing interest: No competing interests

REFERENCES

Arabin, B., and J. H. Stupin. “Overweight and Obesity Before, during and after Pregnancy.” Geburtshilfe und Frauenheilkunde 74.7 (2014): 646–655. PubMed Central. Web.

Carmichael, Suzan L., Sonja A. Rasmussen, and Gary M. Shaw. “Prepregnancy Obesity: A Complex Risk Factor for Selected Birth Defects.” Birth Defects Research. Part A, Clinical and Molecular Teratology 88.10 (2010): 804–810. PubMed. Web.

Iessa, Noha, and Anick Bérard. “Update on Prepregnancy Maternal Obesity: Birth Defects and Childhood Outcomes.” Journal of Pediatric Genetics 4.2 (2015): 71–83. PubMed Central. Web.

Ng, Marie et al. “Global, Regional, and National Prevalence of Overweight and Obesity in Children and Adults during 1980–2013: A Systematic Analysis for the Global Burden of Disease Study 2013.” The Lancet 384.9945 766–781. Web.

Persson, Martina et al. “Risk of Major Congenital Malformations in Relation to Maternal Overweight and Obesity Severity: Cohort Study of 1.2 Million Singletons.” BMJ (2017):j2563. CrossRef. Web.

Competing interests: No competing interests

19 June 2017
Sherneth Heslop Barnett
Registered Nurse, Registered Midwife, Critical Care Nurse.
Sunrise, FL
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